Biotin-PEG9-NHS Ester (CAS: 365441-71-0) is a versatile compound used extensively in bioconjugation, protein labeling, and drug delivery applications. It combines a biotin group, a 9-unit PEG spacer, and an NHS ester group, which enables efficient conjugation with amine-containing molecules. As a result, researchers frequently use it in molecular biology, diagnostics, and therapeutic research.
Key Features:
- Biotin Group: The biotin group binds strongly to avidin or streptavidin, facilitating targeted detection and efficient interactions in biochemical assays.
- PEG9 Spacer: The 9-unit PEG spacer enhances solubility, flexibility, and biocompatibility. Consequently, it improves performance in both biological and aqueous environments.
- NHS Ester Group: The NHS ester reacts selectively with amine groups, allowing easy conjugation with proteins, peptides, and nucleic acids for various applications.
- High Purity: Synthesized with high purity, this compound ensures consistent and reliable results in both research and industrial applications.
- Water Solubility: It dissolves easily in water and polar solvents, thus increasing versatility across a wide range of experimental conditions.
Applications:
- Bioconjugation: Biotin-PEG9-NHS Ester effectively links peptides, proteins, and nucleic acids, driving advancements in drug discovery and diagnostics.
- Protein Labeling: It attaches biotin labels to proteins, enabling easy tracking and detection via avidin or streptavidin.
- Drug Delivery: This compound plays a crucial role in the development of targeted drug delivery systems, thereby enhancing the specificity and effectiveness of therapeutic agents.
- Molecular Biology: Commonly used in assays requiring biotinylation, it facilitates enzyme-linked immunosorbent assays (ELISAs) and Western blots.
- Diagnostic Tools: Moreover, Biotin-PEG9-NHS Ester helps in attaching biomolecules for efficient detection and analysis in biosensors and diagnostic technologies.
Conclusion:
In conclusion, Biotin-PEG9-NHS Ester (CAS: 365441-71-0) serves as a critical tool for bioconjugation, protein labeling, and drug delivery. Its combination of the biotin group, PEG9 spacer, and NHS ester functionality makes it ideal for molecular biology, diagnostics, and therapeutic research. With excellent solubility, high purity, and consistent performance, it proves to be an optimal choice for both research and industrial applications.
