endo-BCN-PEG4-t-butyl ester
| Catalog #: | AP10737 |
| Chemical Formula: | C26H43NO8 |
| Molecular Weight: | 497.62 |
| CAS: | 1807501-83-2 |
| Purity: | 95% |
| Availability: | In Stock |
| SDS: | Download |
| Unit | Price (USD) | |
|---|---|---|
| 50mg | $240.00 | Request quote |
| 100mg | $450.00 | Request quote |
| 250mg | $750.00 | Request quote |
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endo-BCN-PEG4-t-butyl ester
This producct is a heterobifunctional linker containing an endo-bicyclononyne (BCN) group for copper-free SPAAC click chemistry and a t-butyl ester as an acid-labile protecting group. The PEG4 spacer specifically enhances solubility, flexibility, and spacing, making it ideal for bioconjugation, probe development, and drug delivery.
Key Features and Benefits:
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Endo-BCN Group: Enables rapid copper-free click chemistry with azides.
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t-Butyl Ester: Provides acid-labile protection for controlled deprotection.
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PEG4 Spacer: Enhances solubility, hydrophilicity, and steric accessibility.
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Orthogonal Reactivity: Supports multi-step synthesis and controlled conjugation.
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High Purity: Ensures reproducibility in advanced workflows.
Applications:
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Bioconjugation: Combines SPAAC click chemistry with protected ester functionality.
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Drug Delivery: Builds PEGylated scaffolds with controlled release strategies.
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Probe Development: Enables BCN-modified probes with orthogonal handles.
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Material Science: Functionalizes surfaces, polymers, and nanoparticles.
Storage and Handling:
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Storage: Store at –20 °C in a sealed, light- and moisture-protected container.
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Handling: Use anhydrous solvents (e.g., DMF, DMSO); avoid premature deprotection of t-butyl ester.
This product integrates bioorthogonal BCN reactivity with a protected ester in a PEG4 scaffold, specifically offering versatility for controlled conjugation and multifunctional design.