Biotin-PEG6-Hydrazide

Biotin-PEG6-Hydrazide

This product is a high-purity biotinylation reagent with a hydrazide group for aldehyde and ketone coupling, specifically connected by a PEG6 spacer for solubility and flexibility.

Key Features and Benefits

• Biotin Moiety – Enables strong, specific binding to streptavidin and avidin.

• Hydrazide Group – Reacts with aldehydes and ketones to form stable hydrazone linkages.

• PEG6 Spacer – Enhances solubility, reduces steric hindrance, and improves conjugate accessibility.

• High Purity – Suitable for bioconjugation, labeling, and drug delivery workflows.

Applications

• Biotinylation of aldehyde- or ketone-modified biomolecules

• Formation of hydrazone linkages in protein and antibody conjugation

• Probe and diagnostic assay development

• Linker for drug delivery and biomolecule immobilization

Storage & Handling

• Storage: Store at –20 °C, dry, and protected from light.

• Handling: Dissolve in anhydrous solvents (e.g., DMF, DMSO). Avoid repeated freeze–thaw cycles.

This product provides a biotin tag and a hydrazide group on a PEG6 spacer, enabling efficient biotinylation of aldehyde- or ketone-functionalized biomolecules specifically with improved solubility and reduced steric hindrance.