Biotin-PEG4-NHS Ester

Catalog #:	AP10523
Chemical Formula:	C₂₅H₄₀N₄O₁₀S
Molecular Weight:	588.67
CAS:	459426-22-3
Purity:	95%
Availability:	In Stock
SDS:	Download

Unit	Price (USD)
100mg	$175.00	Request quote
250mg	$260.00	Request quote
500mg	$425.00	Request quote
1g	$600.00	Request quote

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Biotin-PEG4-NHS Ester

This product is a high-purity biotinylation reagent featuring an NHS ester for efficient amine coupling and a PEG4 spacer specifically for enhanced solubility and reduced steric hindrance.

Key Features and Benefits

Biotin Moiety – Enables high-affinity binding to avidin/streptavidin systems.
NHS Ester – Reacts efficiently with primary amines under mild conditions.
PEG4 Spacer – Improves solubility, flexibility, and reduces steric interference.
High Purity – Reliable for biochemical, pharmaceutical, and diagnostic use.

Applications

Biotinylation of proteins, peptides, and antibodies
Development of affinity assays and detection systems
Surface labeling and probe conjugation
Diagnostic and therapeutic research tools

Handling

Storage: Store at –20 °C, dry, and protected from light.
Use: Prepare fresh solutions before use. Dissolve in anhydrous DMSO or DMF for coupling reactions. Avoid repeated freeze-thaw cycles.

This product is a PEGylated biotinylation reagent with an NHS ester for amine-reactive labeling, designed with PEG4 specifically to enhance solubility and reduce steric hindrance.

Synonyms: Biotin-PEG4-NHS ester;NHS-PEO4-Biotin;(+)-Biotin-PEG4-NHS ester;(2,5-dioxopyrrolidin-1-yl) 3-[2-[2-[2-[2-[5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoylamino]ethoxy]ethoxy]ethoxy]ethoxy]propanoate;2,5-dioxopyrrolidin-1-yl 17-oxo-21-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)-4,7,10,13-tetraoxa-16-azahenicosanoate;(+)-Biotin-(PEO)4-NHS-propionate;BIOTIN-PEG4-NHSESTER;C25H40N4O10S;21-[(3aS,4S,6aR)-Hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-17-oxo-4,7,10,13-tetraoxa-16-azaheneicosanoic acid 2,5-dioxo-1-pyrrolidinyl ester;15-Biotinamino-4,7,10,13-tetraoxa-pentadecanoic acid succinimidyl ester;(3aS,4S,6aR)-Hexahydro-N-[15-oxo-15-(succinimidyloxy)-3,6,9,12-tetraoxapentadecane-1-yl]-2-oxo-1H-thieno[3,4-d]imidazole-4-pentanamide;2,5-dioxopyrrolidin-1-yl 17-oxo-21-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)-4,7,10,13-tetraoxa-16-azahenicosan-1-oate

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