Biotin-PEG4-Azide

Biotin-PEG4-Azide

This product is a heterobifunctional linker featuring a biotin group for high-affinity avidin/streptavidin binding and a terminal azide for click chemistry. The PEG4 spacer provides solubility, flexibility, and steric accessibility, making it especially effective for probe design, drug delivery, and bioconjugation.

Key Features and Benefits:

• Biotin Moiety: Provides strong and specific binding to avidin/streptavidin systems.

• Azide Group: Supports CuAAC or SPAAC click chemistry with alkynes.

• PEG4 Spacer: Improves solubility and reduces steric hindrance.

• Dual Functionality: Combines biotin affinity with bioorthogonal reactivity.

• High Purity: Ensures reproducibility in sensitive workflows.

Applications:

• Probe Development: Builds biotinylated, click-reactive probes for imaging and diagnostics.

• Drug Delivery: Supports PEGylated scaffolds with avidin-targeting handles.

• Bioconjugation: Links biomolecules through biotin capture and click chemistry.

• Material Science: Functionalizes surfaces and nanoparticles with dual reactivity.

Storage and Handling:

• Storage: Store at –20 °C in a sealed, light- and moisture-protected container.

• Handling: Use anhydrous solvents (e.g., DMF, DMSO) to preserve reactivity.

This product integrates biotin binding with azide reactivity in a PEG4 scaffold, specifically offering versatility for multifunctional conjugation, probe design, and drug delivery.