Biotin-PEG2-Hydrazide

Biotin-PEG2-Hydrazide

This product is a high-purity biotinylation reagent featuring a terminal hydrazide group linked through a short PEG2 spacer. This design specifically allows efficient labeling of aldehyde- or ketone-containing biomolecules, while maintaining biotin’s strong affinity for streptavidin and avidin.

Key Features and Benefits

• Biotin Moiety – Provides high-affinity, specific binding to streptavidin and avidin systems.

• Hydrazide Group – Reacts selectively with aldehydes and ketones for stable hydrazone bond formation.

• PEG2 Spacer – Enhances solubility and reduces steric hindrance in conjugation reactions.

• High Purity – Ensures reliable performance in bioconjugation and analytical applications.

Applications

• Biotinylation of oxidized glycans, proteins, or antibodies

• Conjugation to aldehyde-functionalized biomaterials or surfaces

• Probe development for diagnostics and biosensor platforms

• Labeling for imaging, assay, and drug delivery studies

Storage & Handling

• Storage: Store at –20 °C, dry, and protected from light.

• Use: Dissolve in anhydrous solvents (e.g., DMF, DMSO). Avoid repeated freeze–thaw cycles.

This product is a biotinylation linker with a hydrazide group on a PEG2 spacer, enabling efficient conjugation with aldehyde- or ketone-containing molecules while improving solubility and reducing steric hindrance.