Biotin-PEG2-Azide

Biotin-PEG2-Azide

This product is a heterobifunctional PEG linker containing a biotin moiety, a PEG2 spacer, and a terminal azide group. It specifically enables streptavidin binding and copper-catalyzed or copper-free click chemistry, offering solubility and versatile dual reactivity.

Key Features and Benefits

• Biotin Moiety: Provides strong affinity for streptavidin and avidin systems.

• Azide Group: Reacts with alkynes via CuAAC or SPAAC click chemistry.

• PEG2 Spacer: Enhances solubility while maintaining compact length.

• Dual Reactivity: Combines biotin affinity capture with azide click chemistry.

• High Purity: Ensures reproducibility in labeling and conjugation workflows.

Applications

• Bioconjugation: Links biomolecules with streptavidin and alkyne-modified partners.

• Probe Development: Builds multifunctional probes for imaging and diagnostics.

• Drug Delivery: Provides PEG scaffolds with affinity and click handles.

• Material Science: Functionalizes nanoparticles and surfaces with biotin and azide groups.

Storage and Handling

• Storage: Store at –20 °C in a sealed, light- and moisture-protected container.

• Handling: Use anhydrous solvents such as DMSO or DMF; avoid prolonged moisture exposure.

This product integrates biotin affinity with azide click chemistry in a PEG2 scaffold, specifically offering compact, soluble, and multifunctional conjugation capability.