Biotin-PEG2-aldehyde

Biotin-PEG2-aldehyde

This product is a PEG linker containing a biotin group, a PEG2 spacer, and a terminal aldehyde. It enables streptavidin binding and carbonyl conjugation, making it especially valuable in probe development, detection, and bioconjugation workflows.

Key Features and Benefits

• Biotin Group: Provides strong affinity binding to streptavidin and avidin.

• Aldehyde Group: Couples with amines or hydrazides via reductive amination or oxime ligation.

• PEG2 Spacer: Enhances solubility and minimizes steric hindrance.

• Dual Reactivity: Combines affinity capture with aldehyde-based conjugation.

• High Purity: Ensures reproducible results in sensitive labeling applications.

Applications

• Bioconjugation: Links biotin-binding systems with amine- or hydrazide-modified molecules.

• Probe Development: Builds multifunctional probes for imaging and diagnostics.

• Detection Assays: Provides strong affinity tagging for streptavidin-based systems.

• Drug Delivery: Serves as a PEGylated scaffold with dual reactivity.

Storage and Handling

• Storage: Store at –20 °C in a sealed, light- and moisture-protected container.

• Handling: Use anhydrous solvents such as DMF or DMSO; avoid prolonged exposure to moisture.

This product integrates strong biotin–streptavidin affinity with aldehyde chemistry in a compact PEG2 scaffold, specifically providing a versatile tool for labeling and conjugation.