Biotin-Hydrazide

Catalog #:	AP10490
Chemical Formula:	C₁₀H₁₈N₄O₂S
Molecular Weight:	258.34
CAS:	66640-86-6
Purity:	95%
Availability:	In Stock
SDS:	Download

Unit	Price (USD)
100mg	$60.00	Request quote
250mg	$120.00	Request quote
500mg	$210.00	Request quote
1g	$350.00	Request quote
2 g	$520.00	Request quote

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Biotin-Hydrazide

This product is a high-purity biotin derivative featuring a hydrazide group for selective coupling with aldehydes and ketones. The biotin moiety enables strong, specific binding to streptavidin or avidin, while the hydrazide allows covalent labeling of oxidized glycans, aldehyde-tagged biomolecules, or other carbonyl-containing targets. This makes it especially useful in affinity purification, labeling, and detection workflows.

Key Features and Benefits

Dual Functionality: Biotin for affinity binding, hydrazide for carbonyl conjugation.
High Affinity: Strong interaction with streptavidin/avidin systems.
Specific Reactivity: Targets aldehydes and ketones for stable hydrazone bonds.
High Purity: Suitable for sensitive biochemical applications.

Applications

Affinity purification of carbonyl-containing biomolecules.
Glycoprotein labeling after periodate oxidation.
Biotinylation of aldehyde-tagged proteins and peptides.
Detection in ELISA, Western blotting, and other biotin–streptavidin assays.

Storage and Handling

Storage: Store at –20 °C in a dry, dark place.
Handling: Protect from moisture and light; use under inert atmosphere if possible.

This product is a versatile reagent, especially ideal for labeling, purification, and detection in biochemical assays.

Synonyms: Biotin hydrazide;(+)-Biotin hydrazide;5-((3aS,4S,6aR)-2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanehydrazide;biotin-hydrazide;(+)-Biotin-hydrazide;C10H18N4O2S;Biontin-Hydrazide;5-((3AS,4S,6aR)-2-Oxohexahydro-1H-thieno-[3,4-d]imidazol-4-yl)pentanehydrazide;biotin hydrazone;Biotin-NHNH2;5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanehydrazide;(+)-Biotin hydrazide;Biotin hydrazide;1H-Thieno[3,4-d]imidazole-4-pentanoic acid, hexahydro-2-oxo-,hydrazide, (3aS,4S,6aR)-;5-((3aS,4S,6aR)-2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanehydrazi de;5-(2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanohydrazide;1H-Thieno(3,4-d)imidazole-4-pentanoic acid, hexahydro-2-oxo-, hydrazide, (3aS,4S,6aR)-;5-(2-Hydroxy-3a,4,6,6a-tetrahydro-1H-thieno[3,4-d]imidazol-6-yl)pentanehydrazonic acid;5-[(3aS,4S,6aR)-2-oxo-hexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanehydrazide;1H-Thieno(3,4-d)imidazole-4-pentanoic acid, hexahydro-2-oxo-, hydrazide, (3aS-(3aalpha,4beta,6aalpha))-

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