Biotin-PEG6-amine

Biotin-PEG6-amine

This product is a heterobifunctional linker consisting of a biotin tag, a six-unit PEG spacer, and a terminal primary amine. The biotin enables strong binding to streptavidin and avidin systems, while the amine couples efficiently with carboxyl or activated esters to form stable amide bonds. The PEG6 spacer improves solubility, flexibility, and accessibility, making this reagent especially useful for affinity capture, probe design, and bioconjugation.

Key Features and Benefits

• Biotin Tag: Provides strong, specific binding to streptavidin, avidin, and NeutrAvidin.

• Primary Amine: Couples readily with carboxyls or NHS esters.

• PEG6 Spacer: Enhances solubility and reduces steric hindrance in conjugates.

• Dual Functionality: Combines biotin affinity binding with amine conjugation chemistry.

• High Purity: Produced to ≥95% purity for consistent performance.

Applications

• Affinity Capture: Biotinylates molecules for immobilization on streptavidin-coated surfaces.

• Protein and Antibody Labeling: Attaches biotin tags for detection and purification.

• Probe Development: Builds multifunctional probes for imaging and diagnostics.

• Drug Delivery: Serves as a biotin-functionalized linker for targeted systems.

Storage and Handling

• Storage: Store at –20 °C in a sealed, desiccated container.

• Handling: Dissolve freshly in buffer or solvent; avoid repeated freeze–thaw cycles.

This product integrates strong biotin affinity with amine reactivity on a PEG6 backbone, specifically offering a versatile tool for bioconjugation and probe development.