Biotin-PEG3-amine

Biotin-PEG3-amine

This product is a heterobifunctional PEG3 linker with a biotin moiety and a terminal primary amine. The PEG3 spacer provides hydrophilicity and flexibility, while the biotin enables high-affinity binding to avidin/streptavidin systems, making it an excellent tool for targeted labeling, affinity capture, and bioconjugation.

Key Features and Benefits:

• Biotin Group: Strong affinity binding to avidin and streptavidin proteins.

• Amine Group: Couples efficiently with carboxyls, NHS esters, and electrophiles.

• PEG3 Spacer: Provides compact hydrophilicity with reduced steric hindrance.

• High Purity: Ensures reproducibility in sensitive conjugation workflows.

• Dual Functionality: Combines biotin affinity with amine-based reactivity.

Applications:

• Affinity Labeling: Biotinylation of proteins, peptides, and biomolecules.

• Bioconjugation: Dual-functional linker for targeted labeling strategies.

• Drug Delivery: PEGylated linker enhances solubility and targeting ability.

• Surface Functionalization: Functionalizes nanoparticles, polymers, and biosensors.

Storage and Handling:

• Storage: Store at –20 °C in a dry, light-protected container.

• Handling: Use anhydrous solvents (e.g., DMF, DMSO) to preserve amine reactivity.

This product combines strong biotin binding with amine-based conjugation in a compact PEG spacer, making it especially versatile for biomolecule labeling and targeted delivery.