HyNic PEG2 BCN
| Catalog #: | AP10136 |
| Chemical Formula: | C26H37N5O5 |
| Molecular Weight: | 499.60 |
| CAS: | 1507370-54-8 |
| Purity: | 95% |
| Availability: | In Stock |
| SDS: | Download |
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HyNic PEG2 BCN (CAS: 1507370-54-8) is a bifunctional linker with a 6-hydrazinonicotinamide (HyNic) group and a bicyclo[6.1.0]nonyne (BCN) group connected by a PEG2 spacer. The HyNic group forms stable hydrazone bonds with carbonyl-containing biomolecules, while the BCN group enables copper-free click chemistry with azides through strain-promoted azide-alkyne cycloaddition (SPAAC). The PEG2 spacer improves solubility and flexibility in aqueous environments.
Key Features:
- Functional Groups: HyNic for hydrazone bond formation and BCN for copper-free click chemistry.
- Molecular Formula: C₂₆H₃₇N₅O₅
- Molecular Weight: 499.60 g/mol
- Purity: ≥95%
HyNic PEG2 BCN Applications:
- Bioconjugation: Attaches biomolecules through hydrazone bonding and click chemistry with azides.
- Antibody-Drug Conjugates (ADCs): Acts as a stable linker for drug-antibody conjugation.
- Surface Functionalization: Enables immobilization of biomolecules on surfaces for biosensors and bioassays.
This linker ensures precise and efficient molecular assembly, making it valuable for targeted drug delivery, diagnostics, and chemical biology research.
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