DBCO-acid C6

DBCO-acid C6 CAS:1425485-72-8 is a popular building block and DBCO acid for DBCO derivatization. The acid group can react with amine to form amide bond under coupling conditions in the presence of activators such as EDC, DCC and HATU. DBCO. On the other hand readily react with azide bearing biomolecule through a copper-free click reaction instantly and in high yield.

DBCO-acid C6 has been utilized in the development of novel drug delivery systems, such as hydrogels, nanoparticles, and liposomes. Its unique chemical properties enable the covalent attachment of therapeutic agents, such as drugs, to the DBCO moiety via copper-free click chemistry. The resulting conjugates exhibit enhanced stability, controlled drug release, and improved pharmacokinetic properties, leading to improved therapeutic efficacy and reduced side effects.