Biotin-PEG8-alcohol

Biotin-PEG8-alcohol

This product is a heterobifunctional linker featuring a biotin tag, an eight-unit PEG spacer, and a terminal hydroxyl group. The biotin moiety specifically binds strongly to streptavidin, avidin, and NeutrAvidin, while the hydroxyl group serves as a versatile handle for further chemical modification. The PEG8 spacer improves solubility, flexibility, and biotin accessibility, making this reagent especially valuable for bioconjugation, probe development, and affinity-based applications.

Key Features and Benefits

• Biotin Tag: Ensures high-affinity binding to streptavidin and avidin systems.

• Hydroxyl Group: Provides a modifiable site for additional derivatization.

• PEG8 Spacer: Enhances solubility, spacing, and reduces steric hindrance.

• Versatile Design: Supports flexible conjugation strategies.

• High Purity: Produced to ≥95% purity for reproducible results.

Applications

• Affinity Capture: Immobilizes biomolecules on streptavidin-coated beads, plates, or chips.

• Bioconjugation: Provides a biotin handle for labeling and detection.

• Probe Development: Builds biotinylated probes for imaging and diagnostics.

• Drug Delivery: Functions as a PEGylated linker for targeted delivery systems.

Storage and Handling

• Storage: Store at –20 °C in a sealed, moisture-free container.

• Handling: Prepare fresh solutions; avoid repeated freeze–thaw cycles.

This product combines strong biotin binding with hydroxyl functionality on a PEG8 backbone, providing an especially reliable tool for bioconjugation and assay development.