Biotin-PEG12-alcohol

Biotin-PEG12-alcohol

This product is a heterobifunctional linker with a biotin tag, a PEG12 spacer, and a terminal hydroxyl group. The biotin binds strongly to streptavidin, avidin, and NeutrAvidin while the hydroxyl group serves as a versatile handle for further chemical derivatization. The PEG12 spacer specifically improves solubility, enhances biotin accessibility, and provides long-range flexibility for bioconjugation and assay development.

Key Features and Benefits

• Biotin Tag: Provides high-affinity binding to streptavidin and avidin systems.

• Hydroxyl Group: Offers a modifiable site for further functionalization.

• PEG12 Spacer: Enhances solubility, accessibility, and spacing.

• Versatile Design: Suitable for probes, drug delivery, and bioconjugates.

• High Purity: Produced to ≥95% purity for reliable performance.

Applications

• Affinity Capture: Immobilizes biomolecules on streptavidin-coated plates, chips, or beads.

• Bioconjugation: Introduces biotin handles for labeling and detection.

• Probe Development: Builds biotinylated probes for imaging and diagnostics.

• Drug Delivery: Functions as a linker for targeted therapeutic conjugates.

Storage and Handling

• Storage: Store at –20 °C in a sealed, desiccated container.

• Handling: Prepare fresh solutions; avoid repeated freeze–thaw cycles.

This product combines strong biotin binding with hydroxyl versatility on a long PEG12 backbone, specifically providing a robust tool for advanced conjugation workflows.