Biotin-PEG6-alcohol

Biotin-PEG6-alcohol

This product is a heterobifunctional linker containing a biotin tag, a six-unit PEG spacer, and a terminal hydroxyl group. The biotin moiety binds strongly to streptavidin, avidin, and NeutrAvidin, while the hydroxyl group serves as a versatile handle for further derivatization. The PEG6 chain improves solubility, flexibility, and accessibility, making this reagent especially ideal for bioconjugation, probe development, and affinity-based applications.

Key Features and Benefits

• Biotin Tag: Provides high-affinity binding to streptavidin and avidin systems.

• Hydroxyl Group: Acts as a modifiable site for further functionalization.

• PEG6 Spacer: Enhances solubility and reduces steric hindrance.

• Balanced Design: Offers medium-length spacing with hydrophilic character.

• High Purity: Produced to ≥95% purity for reproducibility.

Applications

• Affinity Capture: Immobilizes biomolecules on streptavidin-coated beads, chips, or surfaces.

• Bioconjugation: Provides biotin handles for labeling and detection.

• Probe Development: Builds biotinylated probes for imaging and diagnostics.

• Drug Delivery: Serves as a functional linker in targeted delivery systems.

Storage and Handling

• Storage: Store at –20 °C in a sealed, desiccated container.

• Handling: Prepare fresh solutions; avoid repeated freeze–thaw cycles.

This product combines strong biotin binding with a modifiable hydroxyl handle on a PEG6 backbone, specifically providing a versatile tool for bioconjugation and assay design.