APN-C3-amine

APN-C3-amine

APN-C3-amine is a high-purity PEG linker with an aminopyridyl nitrile (APN) group for specialized conjugation chemistry and a terminal primary amine for coupling to carboxylic acids or NHS esters. The short C3 alkyl spacer provides a compact, flexible bridge while maintaining high reactivity and minimal steric hindrance, making it suitable for precision bioconjugation in drug delivery, diagnostics, and advanced material applications.

Key Features and Benefits

• APN Functional Group: Enables selective conjugation or labeling strategies in specialized workflows.

• Primary Amine: Couples efficiently to carboxylic acids or activated esters.

• C3 Spacer: Offers a compact, flexible link with minimal steric interference.

• High Purity: Supplied at >95% purity for reproducible, high-yield performance.

• Versatile Reactivity: Suitable for aqueous and organic bioconjugation systems.

Applications

• Protein and Peptide Modification: Introduce APN groups while coupling to amine-reactive partners.

• Drug Delivery Systems: Incorporate as a functional linker for targeted delivery.

• Nanoparticle Functionalization: Add APN handles for advanced surface chemistry.

• Diagnostic Probe Development: Build imaging and sensing agents with specialized reactivity.

• Material Science: Functionalize polymers and biomaterials with unique APN chemistry.

Storage and Handling

• Storage: Store at –20 °C, dry, and protected from light.

• Handling: Use anhydrous solvents such as DMF or DMSO; avoid moisture to maintain reactivity.

APN-C3-amine provides APN reactivity and a primary amine in a short, flexible C3 spacer, enabling targeted, efficient bioconjugation for therapeutic, diagnostic, and material science applications.