APN-C3-NHS ester

APN-C3-NHS ester CAS:1644039-09-7 is a small molecule linker that contains several functional groups, including an amine group, a carboxyl group, and an N-hydroxysuccinimide (NHS) ester group. The amine group can be used to react with other functional groups, such as carboxyl groups or NHS ester groups, to form stable covalent linkages between molecules. The carboxyl group can be used to modify the physicochemical properties of the linker, while the NHS ester group can react with a primary amine to form an amide bond, which can be used to link the linker to other molecules.

APN-C3-NHS ester is commonly used in the field of bioconjugation, which involves the covalent attachment of two or more molecules to form a complex that retains the properties of each individual component. In particular, APN-C3-NHS ester can be used to modify the surface of proteins, peptides, and other biomolecules, allowing for targeted delivery to specific cells or tissues. This modification can improve the pharmacokinetics and efficacy of drugs, as well as reduce their toxicity and immunogenicity.