4-amino-N-(4-(2-cyanoethynyl)phenyl)butanamide

4-amino-N-(4-(2-cyanoethynyl)phenyl)butanamide

4-amino-N-(4-(2-cyanoethynyl)phenyl)butanamide is a bifunctional linker specifically with a cyanoethynyl group and a butanamide bearing a primary amine. Its multifunctional design supports click chemistry, coupling, and derivatization, making it especially valuable for probes, medicinal chemistry, and materials research.

Key Features and Benefits

• Cyanoethynyl Group: Provides a reactive alkyne–nitrile motif for conjugation and extended π-systems.

• Aromatic Core: Offers rigidity and electronic stability for probe or material design.

• Butanamide with Primary Amine: Enables amide bond formation with carboxyl or activated ester groups.

• Multifunctional Reactivity: Supports orthogonal chemistries for advanced conjugation workflows.

• High Purity: Manufactured to ≥95% purity for reliable and reproducible results.

Applications

• Bioconjugation: Couples to biomolecules or polymers through amine–amide linkages or alkyne chemistry.

• Probe Development: Serves as a building block for fluorescent or bioactive probes.

• Medicinal Chemistry: Useful intermediate for heterocyclic or small-molecule drug design.

• Materials Science: Integrates into conjugated polymers and functional materials.

Storage and Handling

• Storage: Store at –20 °C in a sealed container, away from light and moisture.

• Handling: Use freshly prepared solutions; handle under inert conditions for maximum stability.

This product combines cyanoethynyl reactivity with amine–amide functionality, specifically providing a versatile intermediate for synthesis, conjugation, and advanced research applications.